In his message, President Rouhani said he was saddened by the news of over 100 people killed in a Cuban passenger plane.
The president sympathized with the Cuban government and nation and the families of the victims.
He also wished immediate recovery for those injured in the incident.
More than 100 people were killed when a Boeing 737 crashed soon after taking off from Havana on Friday.
There were only three survivors who are said to be in bad conditions.
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